A277 1726 (Medchemexpress

A77 1726

1973-25 each
EUR 489.6

Human IgG antibody Laboratories manufactures the a277 1726 (medchemexpress reagents distributed by Genprice. The A277 1726 (Medchemexpress reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact . Other A277 products are available in stock. Specificity: A277 Category: 1726 Group: (Medchemexpress

True Blue

5(mg
EUR 635

True Blue

5x5(mg
EUR 2705

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(Medchemexpress information

A-966492

HY-10614 50mg
EUR 766.25
Description: A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 nM, respectively.

A-286982

HY-107587 1 mg
EUR 487.02
Description: A-286982 is a potent and allosteric LFA-1/ICAM-1 interaction inhibitor with IC50s of 44 nM and 35 nM in an LFA-1/ICAM-1 binding and LFA-1-mediated cellular adhesion assay, respectively[1][2].

A-784168

HY-108460 10 mg
EUR 270.57
Description: A-784168 is a potent and orally active inhibitor of vanilloid receptor type 1 (TRPV1). Vanilloid receptor type 1 (TRPV1) is a ligand-gated nonselective cation channel that is considered to be an important integrator of various pain stimuli such as endogenous lipids, capsaicin, heat, and low pH. A-784168 has good CNS penetration[1].

A-967079

HY-108463 25mg
EUR 432.91
Description: A-967079 is a selective TRPA1 receptor antagonist with IC50s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS.

A-484954

HY-110096 25mg
EUR 746.76
Description: A-484954 is a highly selective eukaryotic elongationfactor-2 kinase(eEF2K) inhibitor, with an IC50 of 280 nM.

A-770041

HY-11011 5mg
EUR 313.86
Description: A-770041 is a selective and orally active Src-family Lck inhibitor. A-770041 inhibits Lck with an IC50 value of 147 nM with the presence of 1 mM ATP. A-770041 shows 300-fold selective to Lck over Fyn, the other Src family kinase involved in T-cell signaling. A-770041 can be used for the research of acute rejection[1][2].

A-971432

HY-110291 5 mg
EUR 270.57
Description: A-971432 is a potent, selective and orally active sphingosine-1-phosphate (S1P) receptor 5 agonist with IC50s of .362, >10, 0.006 µM for S1P1, S1P3, S1P5 respectively. A-971432 protects blood–brain barrier (BBB) homeostasis. A-971432 reverses age-related cognitive decline. A-971432 has the potential for the research of alzheimer’s disease or multiple sclerosis [1][2].

A-425619

HY-110292 1 mg
EUR 340.91
Description: A-425619, a potent and selective TRPV1 receptor antagonist, is effective in alleviating acute and chronic inflammatory pain and postoperative pain[1].

A-803467

HY-11079 50mg
EUR 248.92
Description: A-803467 is a potent and selective tetrodotoxin-resistant Nav1.8 sodium channel blocker (IC50=8 nM). A-803467 has shown significant anti-nociception in neuropathic and inflammatory pain models. A-803467 enhances the chemosensitivity of conventional anticancer agents through interaction with the ATP-binding cassette subfamily G member 2 (ABCG2) transporter[1][2].

A-933548

HY-113639 Get quote Ask for price
Description: A-933548 is a potent and selective inhibitor of calpain, with a Ki of 18 nM. A-933548 can be used for the research of Alzheimer's disease[1].

A-940894

HY-113669 Get quote Ask for price
Description: A-940894 is a potent histamine H4 receptor antagonist, with Ki values of 7.6 nM (rat H4) and 71 nM (human H4). A-940894 exhibits with anti-inflammatory properties[1].

A-935142

HY-113673 1mg
EUR 617.98
Description: A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. A-935142 enhances hERG current in a complex manner by facilitation of activation, reduction of inactivation, and slowing of deactivation, and abbreviates atrial and ventricular repolarization[1][2].

A-943931

HY-113936 Get quote Ask for price
Description: A-943931 is a potent and selective histamine H4 receptor (H4R) antagonist with pKi values of 4.6, 3.8 nM for human and rat H4R, respectively. A-943931 shows anti-inflammatory and antinociceptive efficacy[1][2].

A-127722

HY-114674 Get quote Ask for price
Description: A-127722 is A 2, 4-dialarylpyrrolidine-3-carboxylic acid ETA selective endothelin receptor (ET receptor) antagonist with IC50 value of 0.36 nM[1].

A-317491

HY-15568 10mM/1mL
EUR 432.91
Description: A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective (IC50>10 μM) over other P2 receptors and other neurotransmitter receptors, ion channels, and enzymes. A-317491 reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux[1][2].

A-385358

HY-16014 10mg
EUR 2002.2
Description: A-385358 is a selective inhibitor of Bcl-XL with Kis of 0.80 and 67 nM for Bcl-XL and Bcl-2, respectively.

A-836339

HY-12761 50mg
EUR 1060.62