Human IgG antibody Laboratories manufactures the a277 1726 (medchemexpress reagents distributed by Genprice. The A277 1726 (Medchemexpress reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact . Other A277 products are available in stock. Specificity: A277 Category: 1726 Group: (Medchemexpress
(Medchemexpress information
A-887826 |
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HY-100080 |
MedChemExpress |
10 mg |
EUR 865.81 |
|
Description: A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo[1]. |
A-205804 |
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HY-100226 |
MedChemExpress |
10 mg |
EUR 523.82 |
|
Description: A-205804 is an orally bioavailable, potent and selective lead inhibitor of E-selectin and ICAM-1 expression, with an IC50 of 20 nM and 25 nM for E-selectin and ICAM-1, respectively. A-205804 can be used in the research of chronic inflammatory diseases[1]. |
A-804598 |
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HY-100483 |
MedChemExpress |
50mg |
EUR 357.15 |
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Description: A-804598 is a CNS penetrant, competitive and selective P2X7 receptor antagonist with IC50s of 9 nM, 10 nM and 11 nM for mouse, rat and human P2X7 receptors, respectively[1]. |
A-841720 |
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HY-103550 |
MedChemExpress |
1 mg |
EUR 80.09 |
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Description: A-841720 is a potent, non-competitive and selective mGlu1 receptor antagonist with an IC50 of 10 nM for human mGlu1 receptor. A-841720 displays 34-fold selectivity over mGlu5 (IC50 of 342 nM), and no significant activity at a range of other neurotransmitter receptors, ion channels, and transporters. A-841720 has the potential for chronic pain research[1][2]. |
A-443654 |
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HY-10425 |
MedChemExpress |
5mg |
EUR 1190.49 |
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Description: A-443654 is a pan-Akt inhibitor and has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM)[1]. |
A-966492 |
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HY-10614 |
MedChemExpress |
50mg |
EUR 766.25 |
|
Description: A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 nM, respectively. |
A-286982 |
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HY-107587 |
MedChemExpress |
1 mg |
EUR 487.02 |
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Description: A-286982 is a potent and allosteric LFA-1/ICAM-1 interaction inhibitor with IC50s of 44 nM and 35 nM in an LFA-1/ICAM-1 binding and LFA-1-mediated cellular adhesion assay, respectively[1][2]. |
A-784168 |
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HY-108460 |
MedChemExpress |
10 mg |
EUR 270.57 |
|
Description: A-784168 is a potent and orally active inhibitor of vanilloid receptor type 1 (TRPV1). Vanilloid receptor type 1 (TRPV1) is a ligand-gated nonselective cation channel that is considered to be an important integrator of various pain stimuli such as endogenous lipids, capsaicin, heat, and low pH. A-784168 has good CNS penetration[1]. |
A-967079 |
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HY-108463 |
MedChemExpress |
25mg |
EUR 432.91 |
|
Description: A-967079 is a selective TRPA1 receptor antagonist with IC50s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS. |
A-484954 |
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HY-110096 |
MedChemExpress |
25mg |
EUR 746.76 |
|
Description: A-484954 is a highly selective eukaryotic elongationfactor-2 kinase(eEF2K) inhibitor, with an IC50 of 280 nM. |
A-770041 |
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HY-11011 |
MedChemExpress |
5mg |
EUR 313.86 |
|
Description: A-770041 is a selective and orally active Src-family Lck inhibitor. A-770041 inhibits Lck with an IC50 value of 147 nM with the presence of 1 mM ATP. A-770041 shows 300-fold selective to Lck over Fyn, the other Src family kinase involved in T-cell signaling. A-770041 can be used for the research of acute rejection[1][2]. |
A-971432 |
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HY-110291 |
MedChemExpress |
5 mg |
EUR 270.57 |
|
Description: A-971432 is a potent, selective and orally active sphingosine-1-phosphate (S1P) receptor 5 agonist with IC50s of .362, >10, 0.006 µM for S1P1, S1P3, S1P5 respectively. A-971432 protects blood–brain barrier (BBB) homeostasis. A-971432 reverses age-related cognitive decline. A-971432 has the potential for the research of alzheimer’s disease or multiple sclerosis [1][2]. |
A-425619 |
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HY-110292 |
MedChemExpress |
1 mg |
EUR 340.91 |
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Description: A-425619, a potent and selective TRPV1 receptor antagonist, is effective in alleviating acute and chronic inflammatory pain and postoperative pain[1]. |
A-803467 |
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HY-11079 |
MedChemExpress |
50mg |
EUR 248.92 |
|
Description: A-803467 is a potent and selective tetrodotoxin-resistant Nav1.8 sodium channel blocker (IC50=8 nM). A-803467 has shown significant anti-nociception in neuropathic and inflammatory pain models. A-803467 enhances the chemosensitivity of conventional anticancer agents through interaction with the ATP-binding cassette subfamily G member 2 (ABCG2) transporter[1][2]. |
A-317491 |
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HY-15568 |
MedChemExpress |
10mM/1mL |
EUR 432.91 |
|
Description: A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective (IC50>10 μM) over other P2 receptors and other neurotransmitter receptors, ion channels, and enzymes. A-317491 reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux[1][2]. |
A-385358 |
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HY-16014 |
MedChemExpress |
10mg |
EUR 2002.2 |
|
Description: A-385358 is a selective inhibitor of Bcl-XL with Kis of 0.80 and 67 nM for Bcl-XL and Bcl-2, respectively. |
