Pro Caspase 1 Antibody

Caspase 1 Assay Kit

20-abx299019
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  • 100 tests
  • 25 tests

Caspase Assay Laboratories manufactures the pro caspase 1 antibody reagents distributed by Genprice. The Pro Caspase 1 Antibody reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact caspase assay. Other Pro products are available in stock. Specificity: Pro Category: Caspase Group: 1 Antibody

Caspase-1 Fluorometric Assay Kit

each
EUR 744

Caspase-1 Fluorometric Assay Kit

each
EUR 248.4

Caspase-1 Fluorometric Assay Kit

each
EUR 1149.6

Caspase-1 Colorimetric Assay Kit

each
EUR 574.8

Caspase-1 Colorimetric Assay Kit

each
EUR 744

Caspase-1 Colorimetric Assay Kit

each
EUR 248.4

Caspase-1 Colorimetric Assay Kit

each
EUR 1149.6

1 Antibody information

Monoclonal Caspase-9 Antibody (Pro), Clone: E23

APG02422G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human Caspase-9 (Pro). The antibodies are raised in Rabbit and are from clone E23. This antibody is applicable in WB and IHC

Monoclonal Caspase-6 Antibody (Pro), Clone: EP1325Y

APG02390G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human Caspase-6 (Pro). The antibodies are raised in Rabbit and are from clone EP1325Y. This antibody is applicable in WB, IHC and IF

Anti-pro Caspase-3 Antibody [SZ02-08]

ET1603-26 100ul
EUR 231
Description: Caspase-3, also known as apopain, SCA-1, Yama and CPP32, is an aspartate-specific cysteine protease that belongs to the ICE subfamily of caspases. Caspase-3 is expressed in cells as an inactive precursor from which the p17 and p11 subunits of the mature caspase-3 are proteolytically generated during apoptosis. The caspase-3 precursor is first cleaved at Asp175-Ser176 to produce the p11 subunit and the p20 peptide. Subsequently, the p20 peptide is cleaved at Asp28-Ser29 to generate the mature p17 subunit. The active caspase-3 enzyme is a heterodimer composed of two p17 and two p11 subunits. At the onset of apoptosis, caspase-3 proteolytically cleaves PARP at an Asp216-Gly217 bond. During the execution of the apoptotic cascade, activated caspase-3 releases SREBP from the membrane of the ER in a proteolytic reaction that is distinct from their normal sterol-dependent activation. Caspase-3 cleaves and activates SREBPs between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase-3 also cleaves and activates caspase-6, -7 and -9. The human caspase-3 gene encodes a cytoplasmic protein that is highly expressed in lung, spleen, heart, liver, kidney and cells of the immune system.

Anti-pro Caspase-7 Antibody [SD20-57]

ET1612-28 100ul
EUR 231
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.

Anti-pro Caspase-7 Antibody [SD20-57]

ET1612-28TR 20ul
EUR 64.35
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.

Anti-pro Caspase-9 Antibody [JJ08-05]

ET1701-22 100ul
EUR 231
Description: Caspase-9 is an enzyme that in humans is encoded by the CASP9 gene. It is an initiator caspase, critical to the apoptotic pathway found in many tissues. Caspase-9 belongs to a family of caspases, cysteine-aspartic proteases involved in apoptosis and cytokine signalling. Apoptotic signals cause the release of cytochrome c from mitochondria and activation of apaf-1 (apoptosome), which then cleaves the pro-enzyme of caspase-9 into the active dimer form. Correct caspase-9 function is required for apoptosis, leading to the normal development of the central nervous system. Caspase-9 has multiple additional cellular functions that are independent of its role in apoptosis. Nonapoptotic roles of caspase-9 include regulation of necroptosis, cellular differentiation, innate immune response, sensory neuron maturation, mitochondrial homeostasis, corticospinal circuit organization, and ischemic vascular injury. Without correct function, abnormal tissue development can occur leading to abnormal function, diseases and premature death. Caspase-9 loss-of-function mutations have been associated with immunodeficiency/lymphoproliferation, neural tube defects, and Li-Fraumeni-like syndrome. Increased caspase-9 activity is implicated in the progression of amyotrophic lateral sclerosis, retinal detachment, and slow-channel syndrome, as well as various other neurological, autoimmune, and cardiovascular disorders.

pro Caspase 3 recombinant monoclonal antibody

A5185 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human pro Caspase 3 for WB, IHC, IF,ELISA

Pro Caspase 7 recombinant monoclonal antibody

A5667 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Pro Caspase 7 for WB ,ELISA

Anti-active+pro Caspase-3 Antibody [SU38-04]

ET1608-64 100ul
EUR 231
Description: Caspase-3 is a caspase protein that interacts with caspase-8 and caspase-9. It is encoded by the CASP3 gene. The CASP3 protein is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6 and 7; and the protein itself is processed and activated by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Caspase-3 is expressed in cells as an inactive precursor from which the p17 and p11 subunits of the mature caspase-3 are proteolytically generated during apoptosis. The active caspase-3 enzyme is a heterodimer composed of two p17 and two p11 subunits.

Monoclonal Caspase-3 Antibody (Pro), Clone: E83-103

APG02401G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human Caspase-3 (Pro). The antibodies are raised in Rabbit and are from clone E83-103. This antibody is applicable in WB and IHC

Caspase 1 Antibody

6687-100 each
EUR 405.6

Caspase 1 Antibody

6687-30T each
EUR 175.2

Caspase 1 antibody

20R-1427 100 ug
EUR 781.2
Description: Rabbit polyclonal Caspase 1 antibody

caspase 1 Antibody

39310-100ul 100ul
EUR 468

Caspase 1 Antibody

E18-5418-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Caspase 1 Antibody

E18-5418-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Caspase 1 Antibody

E38PA1133 100ul
EUR 225
Description: Available in various conjugation types.