The follicular variant of papillary thyroid carcinoma usually presents as a tumor packaged and less common as infiltrative neoplasms partial / non-encapsulated. The shape is packed rarely metastasize to the lymph nodes, whereas infiltrative tumor often harbor nodal metastasis. Profile follicular variant molecules are shown to be close to the group adenoma / carcinoma follicular tumors with high RAS and BRAF mutation rate is very low.

A comprehensive survey of oncogenic mutation in the follicular variant of papillary thyroid carcinoma in accordance with the shape of encapsulated and infiltrative not done. paraffin tissue from 28 patients with packaged and 19 with the follicular variant of infiltrating into the target mass spectrometry genotyping include the most significant oncogenes in thyroid carcinoma: 111 mutations in RET, BRAF, NRAS, HRAS, KRAS, PIK3CA, AKT1 and other related genes. There were no differences in age, gender, tumor size and angioinvasion between encapsulation or infiltrative tumor. infiltrative carcinomas have a higher frequency of extrathyroid extension, positive margins and nodal metastases from encapsulated tumor (P <0.05). The BRAF 1799T> A mutation was found in 5 of 19 (26%) of tumor infiltrating and none of the encapsulated carcinoma (P = 0.007).

Instead, RAS mutations were observed in 10 of 28 (36%) of the encapsulated group (5 NRAS_Q61R, 3 HRAS_Q61, 1 HRAS_G13C and 1 KRAS_Q61R) and only 2 of 19 (10%) of the infiltrative tumors (P = 0.09). One carcinoma packed show PAX8 / PPARgamma rearrangements, whereas infiltrative tumor harbored two RET / PTC fusion. Packed follicular variant of papillary thyroid carcinoma had a molecular profile is very close to the follicular adenoma / carcinoma (high level RAS and BRAF mutation). Infiltrative follicular variant had the opposite molecular profile closer to classical papillary thyroid carcinoma than follicular adenoma / carcinoma (BRAF> RAS mutation). Profile molecule is packaged and infiltrative follicular variant align their biological behavior (ie, nodal metastatic and invasive pattern).

molecular heterozygous genotype showed ataxia-telangiectasia tend to breast cancer.

Approximately 1.4% of the general population are heterozygous carriers of the gene for ataxiatelangiectasia (A-T), an autosomal recessive progressive neurological syndromes in which cancer incidence homozygotes was about 100 times that of the general population’s level. The hypothesis that A-T heterozygotes tend to breast cancer tested with robust statistical method contains an index-based genotyping test molecule. A-T gene carrier status of 775 blood relatives in the family 99 A-T is determined by tracing the A-T gene in each family through flanking DNA markers closely linked.

There were 33 women with breast cancer that can genotype; 25 of them A-T heterozygotes, compared with the expected (odds ratio 3.8, 95% confidence limits from 1.7 to 8.4, one-sided p = 0.0001) 14.9. This suggests that the gene heterozygous A-T predisposition to breast cancer. For 21-onset breast cancer before age 60, the odds ratio was 2.9 (1.1 to 7.6, p = 0.009) and for 12 cases with onset at age 60 or older, the odds ratio was 6.4 (1 , 4 to 28.8, p = 0.002).

Urogenital Tissue Slide (Fallopian Tube-Benign)
11-903-10um	ProSci	10 um	EUR 241.8

Urogenital Tissue Slide (Fallopian Tube-Benign)
11-903-4um	ProSci	4 um	EUR 216.6

cDNA - Human Adult Normal Tissue: Fallopian Tube
C1234115-10	Biochain	10 reactions	EUR 215

Urogenital Tissue Slide (Fallopian Tube-Abnormal)
11-905-10um	ProSci	10 um	EUR 241.8

Urogenital Tissue Slide (Fallopian Tube-Abnormal)
11-905-4um	ProSci	4 um	EUR 216.6

cDNA - Monkey (Rhesus) Normal Tissue: Fallopian Tube
C1534115	Biochain	40 reactions	EUR 578

Total Protein - Human Adult Normal Tissue: Fallopian Tube
P1234115	Biochain	1 mg	EUR 513

Human Urogenital Tissue Slide (Fallopian Tube normal) (5 slides/pk)
HTS-11901	Alpha Diagnostics	1 pk	EUR 343.2

Human Urogenital Tissue Slide (Fallopian Tube Benign) (5 slides/pk)
HTS-11903	Alpha Diagnostics	1 pk	EUR 343.2

Human Urogenital Tissue Slide (Fallopian Tube Abnormal) (5 slides/pk)
HTS-11905	Alpha Diagnostics	1 pk	EUR 343.2

Control sections for FD NeuroApop™ Kit (frozen)
PCS102-	FD Neurotechnologies	each	EUR 87.6

Control sections for FD NeuroApop™ Kit (frozen)
PCS102-2	FD Neurotechnologies	each	EUR 80.54
Description: Best quality products

Frozen Tissue Section - Asthma: Lung
T1236152Ld-1	Biochain	5 slides	EUR 475

Frozen Tissue Section - Lupus: Ovary
T1236183Lup	Biochain	5 slides	EUR 682

Frozen Tissue Section - Lupus: Kidney
T1236142Lup	Biochain	5 slides	EUR 587

Frozen Tissue Section - Lupus: Spleen
T1236246Lup	Biochain	5 slides	EUR 515

Frozen Tissue Section - Lupus: Adrenal
T1236004Lup	Biochain	5 slides	EUR 515

Frozen Tissue Section - Emphysema: Lung
T1236152Ld-3	Biochain	5 slides	EUR 475

Frozen Tissue Section - Pneumonia: Lung
T1236152Ld-4	Biochain	5 slides	EUR 475

Frozen Tissue Section - Lupus: Pancreas
T1236188Lup	Biochain	5 slides	EUR 515

Frozen Tissue Section - Bronchitis: Lung
T1236152Ld-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Tumor: Bone
T1235023	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Lung
T1235152	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Skin
T1235218	Biochain	5 slides	EUR 330

Frozen Tissue Section - hypertension: Vein
T1236020Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Tumor: Brain
T1235035	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Colon
T1235090	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Liver
T1235149	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Ovary
T1235183	Biochain	5 slides	EUR 330

Frozen Tissue Section - Lupus: Spinal Cord
T1236234Lup	Biochain	5 slides	EUR 515

Frozen Tissue Section - hypertension: Heart
T1236122Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Tumor: Breast
T1235086	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Kidney
T1235142	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Rectum
T1235206	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Testis
T1235260	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Uterus
T1235274	Biochain	5 slides	EUR 330

Frozen Tissue Section - hypertension: Artery
T1236013Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - hypertension: Kidney
T1236142Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Tumor: Adrenal
T1235004	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Bladder
T1235010	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Parotid
T1235190	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Stomach
T1235248	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Thymoma
T1235264	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Thyroid
T1235265	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Lymphoma
T1235161	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Pancreas
T1235188	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Prostate
T1235201	Biochain	5 slides	EUR 330

Frozen Tissue Section - Human Tumor: Esophagus
T1235106	Biochain	5 slides	EUR 330

Frozen Tissue Section - Arteriosclerosis: Aorta
T1236012Hd-4	Biochain	5 slides	EUR 1060

Frozen Tissue Section - Arteriosclerosis: Artery
T1236013Hd-4	Biochain	5 slides	EUR 1060

Frozen Tissue Section - Human Adult Normal: Lung
T1234152	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Skin
T1234218	Biochain	5 slides	EUR 343

Frozen Tissue Section - Alzheimer's Disease: Brain
T1236035Alz	Biochain	5 slides	EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain
T1236035Par	Biochain	5 slides	EUR 475

Frozen Tissue Section - Dementia: Brain: Thalamus
T1236079Dem	Biochain	5 slides	EUR 475

Frozen Tissue Section - Lupus: Heart: Pericardium
T1236133Lup	Biochain	5 slides	EUR 515

Frozen Tissue Section - Pulmonary embolism: Lung
T1236152Ld-5	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Adult Normal: Brain
T1234035	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Colon
T1234090	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Heart
T1234122	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Liver
T1234149	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Ovary
T1234183	Biochain	5 slides	EUR 629

Frozen Tissue Section - Human Adult Normal: Penis
T1234194	Biochain	5 slides	EUR 343

Frozen Tissue Section - Arrhythmia, infarct: Heart
T1236122Hd-1	Biochain	5 slides	EUR 475

Frozen Tissue Section - Liver Cirrhosis: Prostate
T1236201Lcs	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Adult Normal: Breast
T1234086	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Retina
T1234110	Biochain	5 slides	EUR 529

Frozen Tissue Section - Human Adult Normal: Kidney
T1234142	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Rectum
T1234206	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Spleen
T1234246	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Testis
T1234260	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Throat
T1234263	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Uterus
T1234274	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Vagina
T1234283	Biochain	5 slides	EUR 343

Frozen Tissue Section - Lupus: Blood Vessel: Artery
T1236013Lup	Biochain	5 slides	EUR 515

Frozen Tissue Section - Depression: Brain: Thalamus
T1236079Dep	Biochain	5 slides	EUR 475

Frozen Tissue Section - Liver Cirrhosis: Esophagus
T1236106Lcs	Biochain	5 slides	EUR 475

Frozen Tissue Section - Dementia: Brain: Frontal Lobe
T1236051Dem	Biochain	5 slides	EUR 475

Frozen Tissue Section - Dementia: Brain: Hippocampus
T1236052Dem	Biochain	5 slides	EUR 883

Frozen Tissue Section - Human Adult Normal: Adipose
T1234003	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Adrenal
T1234004	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Bladder
T1234010	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Trachea
T1234160	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Parotid
T1234190	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Stomach
T1234248	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Appendix
T1234006	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Pancreas
T1234188	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Placenta
T1234200	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Prostate
T1234201	Biochain	5 slides	EUR 343

Frozen Tissue Section - Depression: Brain: Frontal Lobe
T1236051Dep	Biochain	5 slides	EUR 475

Frozen Tissue Section - Depression: Brain: Hippocampus
T1236052Dep	Biochain	5 slides	EUR 883

Frozen Tissue Section - Human Adult Normal: Esophagus
T1234106	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Diaphragm
T1234169	Biochain	5 slides	EUR 343

Frozen Tissue Section - Dementia: Brain: Parietal Lobe
T1236066Dem	Biochain	5 slides	EUR 475

Frozen Tissue Section - Alzheimer's Disease: Brain: Pons
T1236071Alz	Biochain	5 slides	EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Pons
T1236071Par	Biochain	5 slides	EUR 475

Frozen Tissue Section - Dementia: Brain: Temporal Lobe
T1236078Dem	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Pons
T1234071	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Lymph Node
T1234161	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Epididymis
T1234105	Biochain	5 slides	EUR 343

Frozen Tissue Section - Dementia: Brain: Occipital Lobe
T1236062Dem	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Adult Normal: Spinal Cord
T1234234	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Gallbladder
T1234118	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Parathyroid
T1234189	Biochain	5 slides	EUR 758

Frozen Tissue Section - Depression: Brain: Parietal Lobe
T1236066Dep	Biochain	5 slides	EUR 475

Frozen Tissue Section - Depression: Brain: Temporal Lobe
T1236078Dep	Biochain	5 slides	EUR 475

Frozen Tissue Section - Congenital heart disease: Heart
T1236122Hd-3	Biochain	5 slides	EUR 475

Frozen Tissue Section - Congestive Heart Failure: Heart
T1236122Hd-6	Biochain	5 slides	EUR 794

Frozen Tissue Section - hypertension: Heart Atrium, left
T1236126Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Depression: Brain: Occipital Lobe
T1236062Dep	Biochain	5 slides	EUR 475

Frozen Tissue Section - hypertension: Heart Atrium, right
T1236127Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Multiple Sclerosis Disease: Brain
T1236035Msc	Biochain	5 slides	EUR 475

Frozen Tissue Section - Alzheimer's Disease: Brain: Amygdala
T1236036Alz	Biochain	5 slides	EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Amygdala
T1236036Par	Biochain	5 slides	EUR 475

Frozen Tissue Section - Alzheimer's Disease: Brain: Thalamus
T1236079Alz	Biochain	5 slides	EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Thalamus
T1236079Par	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Amygdala
T1234036	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Midbrain
T1234059	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Thalamus
T1234079	Biochain	5 slides	EUR 343

Frozen Tissue Section - Alzheimer's Disease: Brain: Pituitary
T1236068Alz	Biochain	5 slides	EUR 883

Frozen Tissue Section - Parkinson's Disease: Brain: Pituitary
T1236068Par	Biochain	5 slides	EUR 883

Frozen Tissue Section - hypertension: Heart Ventricle, left
T1236138Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Adult Normal: Ductus Deferens
T1234100	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Skeletal Muscle
T1234171	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Small Intestine
T1234226	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Diabetic Diseased Tissue: Eye
T1236108Dia	Biochain	5 slides	EUR 662

Frozen Tissue Section - Alzheimer's Disease: Brain: Cerebellum
T1236039Alz	Biochain	5 slides	EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Cerebellum
T1236039Par	Biochain	5 slides	EUR 475

Frozen Tissue Section - hypertension: Heart Ventricle, right
T1236139Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Brain Stem
T1234075	Biochain	5 slides	EUR 343

Frozen Tissue Section - Alzheimer's Disease: Brain: Frontal Lobe
T1236051Alz	Biochain	5 slides	EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Frontal Lobe
T1236051Par	Biochain	5 slides	EUR 475

Frozen Tissue Section - hypertension: Interventricular Septum
T1236130Hd-2	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Cerebellum
T1234039	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Diabetic Diseased Tissue: Lung
T1236152Dia	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Skin
T1236218Dia	Biochain	5 slides	EUR 475

Frozen Tissue Section - Alzheimer's Disease: Brain: Hippocampus
T1236052Alz	Biochain	5 slides	EUR 883

Frozen Tissue Section - Human Adult Normal: Brain: Frontal Lobe
T1234051	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Blood Vessel: Vein
T1234020	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Optic Nerve
T1234064	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Heart: Atrium (left)
T1234126	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Hippocampus
T1234052	Biochain	5 slides	EUR 758

Frozen Tissue Section - Human Adult Normal: Heart: Pericardium
T1234133	Biochain	5 slides	EUR 343

Frozen Tissue Section - Human Diabetic Diseased Tissue: Brain
T1236035Dia	Biochain	5 slides	EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Colon
T1236090Dia	Biochain	5 slides	EUR 475

Thus the risk of breast cancer for women heterozygous A-T is not limited to young women, but appears higher in old age. Of all breast cancers in the United States, 6.6% can occur in women who are A-T heterozygotes. This proportion was some great times from the approximate proportion of BRCA1 mutation carriers in breast cancer cases with onset at any age.